LifeQuest Centre for Reproductive Medicine

Sperm Chromatin structure is an area of interest at LifeQuest. We have embarked on a controlled, randomized trial with the Urology department at Mount Sinai Hospital in Toronto. During this trial, we are hoping to measure and compare sperm chromatin structure of ejaculated and testicular sperm specimens so that we may predict the quality of a specimen used for intracytoplasmic sperm injection (ICSI). Measuring chromatin structure shows the susceptibility of the sperm to damage. Recent literature has shown high levels of chromatin damage in the sperm can adversely affect embryo quality and implantation success.